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YK-11 is more than just a SARM

YK-11 is more then just a SARM

YK-11 is possibly the most powerful selective androgen receptor modulators currently on the market. But it is different from SARMs like MK-2866, RAD-140, and LGD-4033 in a couple of ways.

For instance, it is the only modern SARM that isn’t non-steroidal. YK11 closely resembles the structure of DHT (Dihydrotestosterone), a well known synthetic anabolic steroid.

Yk 11 molecular structure
Molecular structure of YK-11

The close resemblance to DHT on a molecular level has sparked debate on the question if YK11 should actually be considered a SARM. Some would argue that it is in fact a synthetic androgenic anabolic steroid.

YK-11 is somewhat of an usual SARM for another reason, which is the fact that it is a myostatin inhibitor.

How does YK-11 work?

Of all the SARMs currently on the market, YK11 is the one that has the least amount of research data. There isn’t any clinical data available to support the claims about the use of this compound and the associated side effects.

Most of what is known about the way that YK11 works, is based on the available research on a cellular level. Because of the popularity of this compound among bodybuilders, there is a fair amount of user reports.


Similar to other SARMs, YK11 binds to the androgen receptors in a tissue-selective manner. Because it binds to the androgen receptors in skeletal muscles it has strong anabolic properties, comparable to that of androgenic anabolic steroids.

YK-11 AND Myostatin inhibition

Some of the basic research mentioned consisted of cellular testing in order to find out about the basic method of action. The results show that YK 11 simply aims to increase follistatin levels. Follistatin is another naturally occurring protein in the human body which helps keep myostatin in check.

When follistatin is raised, myostatin level is inhibited. Inhibition of myostatin results in increased muscle mass and improved strength.


While there are minimal studies on the use of humans, we do know that YK11 has strong anabolic effects in animals.

This study shows that mice that have low levels of myostatin have twice the amount of muscle mass compared to mice that have high levels of myostatin.

Some of the possible benefits associated with the use of YK11 are:

  • Rapid muscle growth
  • Improved strength
  • Increased sex drive

The most obvious benefit of YK11 is without a doubt rapid muscle growth. Reports of 6 to 8 kg of increased muscle mass from an 8-week cycle are not uncommon. The added muscle mass is said to be maintainable after the cycle.

YK-11 benefits

YK11 side effects

Because there aren’t any studies on the safety of YK11 use in humans, we have to rely on user reports for info about the possible side effects of this SARM.

While most users report little to no side effects, others report quite a lot of unwanted side effects. The conclusion is that the side effects vary from person to person.

Some of the potentional side effects associated with the use of YK-11 are:

  • Testosterone suppression
  • Mild liver toxicity
  • Increased aggression
  • Joint and tendon pain

The most obvious side effect of YK11 is testosterone suppression, which is common with most SARMs. Some sort of PCT is therefore highly recommended with this SARM.


To summarize, YK-11 is a powerful myostatin inhibitor that is able to lead to rapid muscle growth and increased strength.

While it isn’t approved for human consumption by the FDA, it is used a lot by body builders because of the strong performance enhancing effects it has.


HQSARMS offers YK-11 in the form of a liquid solution as well as in raw powder form.