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LGD-4033 Ligandrol

What is LGD-4033?

LGD 4033, also known as Ligandrol, is a highly popular, orally active Selective Androgen Receptor Modulator (SARM). SARMs are a group of compounds that are actively being researched as a possibly safer alternative to androgenic anabolic steroids.

LGD 4033 is regarded as one of the strongest non-steroidal SARMs. Along with MK-2866 (Ostarine), it is also one of the few SARMs that have been through clinical trials. Studies show that Ligandrol is effective and well-tolerated.

How does LGD-4033 work?

Like all SARMs, Ligandrol works by binding to the androgen receptors in a tissue-selective manner. This means it has similar benefits that steroids do but with less side effects.

LGD 4033 works by binding to the androgen receptors in skeletal muscle. As a result, it exerts anabolic effects that increase muscle mass and bone density.

But unlike their steroid counterparts, SARMs have little to no affinity for the androgen receptors in organs such as the prostate, liver, and prostate. As a result, they have fewer unwanted side effects than AAS.

LGD-4033 benefits

Ligandrol has a number of incredible benefits, including:

  • Increased muscle mass
  • Improved strength
  • Faster recovery
  • Improved bone health

Increased muscle masS

One study that was carried out among 76 healthy men showed that test subjects made impressive gains, even on a low dose. When given only 1.0mg a day, they gained close to 3lbs of lean muscle mass in only 3 weeks.

This makes LGD 4033 the most effective SARM with respect to increasing muscle mass, having anabolic properties that are 8 times stronger than those of Ostarine (MK-2866).

Lgd 4033 Clinical Trial1
This chart shows the increase in lean muscle mass over a period of
21 days on various doses and a controlled placebo study group.

Improved strength

Besides increasing muscle mass, Ligandrol also improves strength. You can expect to be able to lift heavier weights and increase the intensity and duration of a training session. LGD 4033 is one of the strongest SARMs when it comes to anabolic activity.

Faster recovery

Recovery is a very important factor in training. Muscles aren’t built in the gym but in bed. This means that faster recovery equals better results.

One of the most noticeable benefits of LGD-4033 is a shorter recovery time.

Improved bone health

Preventing bone loss and increasing bone formation is key to protecting against osteoporosis. The standard therapy for osteoporosis is far from ideal. SARMs may prove to be a safer option for increasing bone strength and bone healing.

The androgen receptors (AR) SARMs are crucial for maintaining bone mass. They allow for the healing of fractures.

LGD 4033 studies by Viking Therapeutics are currently underway. This SARM may see approval in the future for improving recovery after hip fracture surgery. Initial research on LGD-4033 has proven to be effective in encouraging the bone formation and preventing bone loss. 

LGD-4033 dosage

The most common dose for LGD 4033 is between 5mg and15 mg, with 10mg considered to be the sweet spot. To build lean muscle mass and increase strength, 10mg per day is suffient. Higher dosages will increase the possibility of unwanted side effects.

Because LGD-4033 has an active half-life of 24 to 36 hours, it only has to be taken once a day.

Ligandrol for bulking

To increase muscle mass and strength, take 10 mg a day for 8 weeks.

Ligandrol for cutting

To shred body fat without loosing muscle mass, take 5 to 10 mg for 6 to 8 weeks.

Ligandrol side effects

Studies on LGD-4033 show that this SARM is well tolerated at the dosages that are studied. The most common side effects of Ligandrol are nausea, headaches, water retention, and fatigue. It can also lead to testosterone suppression which is one of the major side effects. 

Testosterone suppression

The most obvious side effect of LIgandrol is testosterone suppression, which can result in reduced libido and fatigue. To restore natural testosterone production, we strongly recommend some form of PCT (Post Cycle Therapy).

Is LGD-4033 legal?

A lot of people aren’t sure if LGD-4033 and other SARMs are legal. The truth is that Ligandrol and the other SARMs are not approved for human consumption by the FDA. This doesn’t mean that they are illegal, but that they can only be sold as “research chemical”.

For more information about the legal status of SARMs, please read our article: Are SARMs legal in Europe?

LGD-4033 half-life and cycle length

LGD 4033 has a long active half-life of 24 to 36 hours. As a result, it is usually taken just once a day. The most common dosage for Ligandrol is 10 mg per day for men and 5 mg per day for women, over a period of 6 to 8 weeks.

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Ligandrol cycle for men
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A closer look at Ligandrol

Clinical trials

According to a clinical trial conducted at the Boston Medical Center’s Section of Endocrinology, Ligandrol can help improve lean body mass and muscle strength.

From another study conducted in January 2013, we know that Ligandrol increases lean muscle mass.

Use in sport

Because of the performance-enhancing effects, LGD-4033 is considered doping by both the WADA and the USDA. As such, Its use is strictly forbidden in professional sports. Several athletes have been caught using LIgandrol and have been banned as a result.

“SARMs have shown superior side effect profiles compared with anabolic steroids, which arguably makes them attractive for use by individuals seeking an unfair advantage over their competitors”

Long-term side effects

SARMs such as Ligandrol are very popular among bodybuilders and athletes. But it is important to keep in mind that none of the SARMs are approved for human consumption by the FDA. We simply do not know if LGD 4033 is safe in the long term because there isn’t enough evidence available.

What is the best place to buy LGD-4033 LIGANDROL? provides Ligandrol in the form of a solution and as raw powder.