RAD 140 was first developed in 2011, originally as a possible treatment for muscle wasting and breast cancer. Because research shows that this SARM has possible neuro-protective properties, there is ongoing research about the role it could possible play with Alzheimer’s disease.
The first human trial of RAD-140 has been conducted and finished in 2020. https://cancerres.aacrjournals.org/content/80/4_Supplement/P5-11-01
HOW DOES RAD140 WORK?
RAD140 (Testolone) is a SARM (Selective Androgen Receptor Modulator). Just like other SARMS, it works by binding to the androgen receptors in selective tissue, specifically in skeletal muscles. As a result, it can produce many of the same benefits as androgenic anabolic steroids (AAS).
RAD140 works by selectively stimulating androgen receptors in the body. For instance, It targets receptors in the muscles and bones. But it has had little to no observed effect on the reproductive organs.
This compound stimulates muscle growth by promoting the development of muscle cells and proteins.
Because RAD-140 doesn’t affect the androgen receptors in organs like the prostate, it doesn’t have the same side effects that are associated with steroids. This doesn’t mean that it is free from unwanted side effects, but they are fairly limited when compared to those of AAS.
RAD-140 vs. LGD-4033
Based on the available clinical research we know that Testolone is more potent than other SARMs such as LGD-4033 and MK-2866. Especially when it concerns its effects on increasing muscle mass, it is one of the strongest SARMs around.
RAD 140 is one of the newer SARMs, and therefore it has been less extensively researched. In fact, the first human trial on RAD 140 has been conducted only recently.
But this hasn’t stopped it from gaining a massive amount of popularity among bodybuilders and athletes. The reason for this is simple: It is highly effective at building mass.

BENEFITS OF RAD 140
This particular SARM is associated with a wide range of effects and possible benefits, of which some have more anecdotal proof than others. The most common benefits associated with RAD140 are:
- The potential to increase muscle mass on a caloric surplus
- Limiting muscle wasting when used during a caloric deficit
- Increasing bone density
- Enhanced endurance and stamina
RAD 140 INCREASE MUSCLE MASS
By targeting the androgen receptors in skeleton muscles, Testolone has the ability to increase muscle mass as well as strength without affecting the prostate or raising blood pressure. Since it does not aromatize or convert to DHT, it doesn’t come with the common negative side effects associated with androgenic anabolic steroids.
PREVENT MUSCLE WASTE
For the same reason that testolone can help to increase muscle mass it can also prevent muscle waste when on a caloric deficit.
INCREASED BONE DENSITY
As with all other SARMs, over time RAD-140 will improve the mineral density of your bones. You may even find that the compound prevents and aids recovery of previous bone injuries.
ENHANCED ENDURANCE AND STAMINA
Another benefit of this SARM, is that it enhances performance. Most importantly, Testolone improves endurance and increases stamina.
RAD-140 Testolone liquid 10mg/ml 30ml
SIDE EFFECTS of Testolone
RAD doesn’t have the same side effects that anabolic steroids do. More accurately, the severity of the side effects is less. But this does not mean that they are non-existing. In summary, the most common side effects are consistent with higher testosterone levels:
- Increased aggression.
- Increased hair growth in women.
- Increase in libido.
RAD 140 AND Suppression
Of all the SARMs known, RAD140 causes the most amount of suppression in natural testosterone levels. However, these will still be fairly limited when compared to androgenic anabolic steroids.
Although testosterone levels will usually recover in a short amount of time, many users prefer to take some form of PCT after cycling on testolone, just to be on the safe side.
Questions about TESTOLONE
RAD140 is very soluble in DMSO, PEG-400 and to a lesser extent in Ethanol.
Testolone is active from a dosage as low as 1 mg. The most common dose lies between 5 mg and 20 mg a day, with 10 mg as the sweet spot.
The actual half-life of RAD is 60 hours, according to the first human trial that finished in 2020.