What are the benefits of Ostarine? What dosage should I take? Does it have any side effects? We will answer these and many more questions in this article.
What is Ostarine?
Ostarine is also known as MK-2866 or Enobosarm. It is a SARM which is short for selective androgen receptor modulator. It mimics the effects of testosterone, by binding to the androgen receptors in specific types of tissue.
Research into MK-2866 started in the early 2000’s and it is currently in phase 3 of human trials. Although it has yet to be approved by the FDA for human consumption, it is highly popular among athletes and bodybuilders.
What does Ostarine do to the body?
Just like other SARMs, Ostarine targets the androgen receptors (AR) in a similair fashion as androgenic anabolic steroids. But, unlike steroids it only targets the receptors in skeletal muscle and not in the organs.
As a result, it provides many of the benefits of steroids, including an increase in lean muscle mass. But it doesn’t have the unwanted side effects that come with the use of steroids.
What is MK-2866 used for?
Ostarine MK-2866 is used to prevent muscle and bone wasting disease (and its potential treatments).
However, it is most popular among bodybuilders and athletes because of the benefits it has in the gym.
- Building muscle/muscle growth – Ostarine can do a lot more than prevent muscle loss/muscular dystrophy. It can also help you to gain lean muscle mass and reduce body fat.
- Lean muscle – When bodybuilding with MK-2866, you won’t experience the same amount of weight gain as with steroids. But you will gain strictly lean muscle mass, without the risk of water retention or gynaecomastia.
- Muscle recovery – this is particularly important for workouts because the faster you recover; the quicker you’ll be able to get back into the gym.
- Joints and tendons – its protective properties – namely its ability to guard your joints, tendons and bone tissues – have made this SARM particularly popular amongst athletes.
- Bone health – the loss of bone-protective sex hormones as we age can result in poor bone health and even osteoporosis. Increasing muscle mass can help to reduce the risk of bone fractures and ensure a speedy recovery.
Ostarine helps by mimicking testosterone in your muscles and bones, providing support to your skeletal system and in the healing of fractures. It is also beneficial in the prevention of bone diseases.
Ostarine is developed to imitate the effects of anabolic steroids, but without the adverse side effects. It was originally designed to help people with muscle-wasting diseases such as osteoporosis, as it binds to the androgen receptors.
It did not take long for athletes and other gym fanatics to discover the benefits, and it is currently the most popular SARM on the market.
However, most users of SARM MK-2866 report the following physical benefits:
- Improvement in muscle mass
- Faster recovery between trainings
- Higher bone density
- Reduced risk of fractures and injuries
- Maintaining muscle mass during a caloric deficit
Improvement in muscle mass
Multiple studies have shown that Ostarine can increase lean muscle mass at dosages as low as 1mg per day. A recent study from 2020 showed that both MK-2866 and Ligandrol had shown positive effects of lean muscle mass.
When used during a caloric deficit, it helps to maintain muscle mass.
Improve strength and performance
Next to gaining muscle, most studies showed an improvement in physical performance as well.
Most users who took Ostarine for a cycle of 8-12 weeks noticed an increase in strength and also improved performance while working out.
Higher bone density
Ostarine has been developed for the treatment of osteoporosis and other diseases that cause bone mass loss. MK-2866 is praised because it prevents bone loss by increasing the density of bone minerals.
Is Ostarine legal?
The legal status of Ostarine is the same as any other SARM. It can be legally sold as a research chemical.
Since the FDA has not approved it for human consumption, it is illegal when marketed as a supplement.
Read all about the legality of SARMS in our blog post: Are SARMS legal in Europe?
It’s important to know, however, that Ostarine, as well as the other SARMs, are prohibited in competitive sports.
Ostarine is listed as a banned substance by almost all sports bodies including the Olympics as well as organisations such as:
This is because of the obvious unfair advantages this compound provides, such as increased strength, muscle, and endurance.
Does Ostarine have side effects?
Research and anecdotal reports have both shown that MK-2866 usually doesn’t cause any adverse side effects.
However, some studies suggest that taking Ostarine for a longer period of time could lead to serious health problems.
Reported side-effects associated with the use of Ostarine include:
- Back Pain
- High Blood Pressure
- Suppress testosterone
- Liver Injury
Does Ostarine lower testosterone?
Anecdotal evidence has shown that Ostarine lowers testosterone levels when used for an extended period of time in high dosages.
So yes, technically MK-2866 will cause some suppression. But the amount of suppression is very low, compared to more potent SARMs, such as RAD-140 and LGD-4033.
Remember to stick to normal dosages and cycle lengths to ensure minimal suppression.
MK 2866 Dosage
During clinical trials, the effective dosage of MK 2866 proved to be as low as 1 mg. However, the dosages used by bodybuilders and athletes are a lot higher, ranging from 5 to 30 mg per day.
The most common dose for Ostarine is 10 mg per day for women and 20 mg per day for men.
MK 2866 cycle length
The most common cycle length for MK 2866 is 8 weeks. It is possible to extend your cycle for a few weeks if you feel good after the end of your 8-week cycle.
We will give an example of 2 possible Ostarine cycles:
|1 – 8||15 mg per day|
This is a great cutting cycle. Ostarine at this dosage is very safe and will allow you to keep on all of your muscle mass while you are cutting.
|1 – 8||20 mg per day|
Ostarine at this dosage will be great for bulking. You will gain a lot of muscle mass and will most likely lose fat at the same time. Remember to eat at maintenance or a slight calorie surplus.
Half-life of Ostarine
The half-life of Ostarine is 24 hours, which means it is sufficient to take it in a single dose once per day. It really doesn’t matter if you take it in the morning or evening, as long as you stick to 24 hour intervals.
Some users prefer to split the dosage into two parts, taking half of the dose in the morning and half in the evening.
Stacking Ostarine for cutting
Since Ostarine is a mild compound, you can stack it with pretty much any SARM. A great stack for cutting combines Ostarine with Cardarine.
In conclusion, Ostarine is a great compound for beginners and advanced lifters. It has great benefits, like promoting lean muscle gain and fat loss, as well as remarkable effects on recovery.
It is the most-researched SARM available, and is generally considered mild in its actions and side-effects.
Frequently asked questions about Ostarine
Ostarine is the most popular and widely used SARMs. It has many of the same benefits of androgenic steroids, but doesn’t have the same side effects.
Ostarine has an active half-life of 24 hours, which means that 50% of MK2866 is out of your system after a day. It is therefore taken once a day.
Ostarine (MK-2866) is legal to buy in every country in the world, as long as it is intended for research purposes. Because it is not FDA approved for human consumption, it can not be sold as a supplement. MK 2866 is considered doping by all major sport associations and it’s use in professional sports is therefore illegal.
Ostarine suppresses your natural hormone levels. While it’s not as suppressive as other SARMs, such as RAD-140 or LGD-4033, it most definitively suppresses your natural testosterone.
MK-2866 is not considered to be the most potent SARM around, but it is the SARM that we have the most data on. It is very versatile and is very effective while having very few side effects.